Epithelial Proliferation following the Intrabronchial Insufflation of Acid
نویسندگان
چکیده
The damage caused by the introduction of acid into the pulmonary parenchyma is repaired rapidly. The depth of the necrosis determines which elements will participate in the repair. If epithelium alone is injured, epithelium alone takes part in the repair. When the damage involves the deeper tissue, organization by granulation competes with and impedes the development of the epithelium. An overproduction of the epithelium occurs and may form bronchiolar polypi or extend into the peribronchial tissue.
منابع مشابه
Effect of Intrabronchial Insufflation of Acid
Acid administered to rabbits by intrabronchial insufflation causes an immediate and extreme damage of the lung tissue. Within certain limits the degree and extent of the injury vary according to the concentration of the acid. With the greater concentrations death occurs promptly, almost immediately, and the lethal process has associated with it a decreased permeability of the pulmonary vessels....
متن کاملThe Reaction of the Lungs to the Intrabronchial Insufflation of Killed Virulent Pneumococci and of Plain Sterile Bouillon
The experiments show that intrabronchial insufflation of a culture of virulent pneumococcus killed by heat and still containing stainable organisms produces an inextensive, mild, patchy, superficial inflammation of the lung tissue bearing no similarity to the lesions produced by the living pneumococcus, and that insufflation of sterile bouillon causes a pronounced congestion of the lung tissue ...
متن کاملEffect of Intrabronchial Insufflation of Solutions of Some Inorganic Salts
Intrabronchial injections of isotonic as well as of hypotonic solutions of sodium chloride or even of distilled water cause no pulmonary lesions. Intrabronchial injections of mercuric chloride even in a dilution of 1:10,000 cause a marked pulmonary lesion. The lesion is not of an inflammatory character; it consists of congestion, formation of thrombi, and hemorrhage. Intrabronchial injections o...
متن کاملExperimental Bronchopneumonia by Intrabronchial Insufflation
When intrabronchial insufflation of pure cultures of the streptococcus or of the influenza bacillus is properly carried out, it produces without fail a pneumonic lesion. This lesion is similar in its nature to the one known in human pathology as bronchopneumonia, and differs materially from the pneumonic lesion produced experimentally by the intrabronchial insufflation of pure cultures of the p...
متن کاملPneumonic Lesions Made by Intrabronchial Insufflation of Non-virulent Pneumococci
The intrabronchial insufflation of a non-virulent pneumococcus causes, like the insufflation of a virulent pneumococcus, the development of an exudate in the lungs which, in general, leaves the framework unaffected, and the lesion presents the gross appearance of a lobar pneumonia. It differs, however, materially from the pneumonia produced by virulent pneumococci in the important points that t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 32 شماره
صفحات -
تاریخ انتشار 2003